This paper employs a proprietary data set on commodity producers’ profit margins (PPMG) and establishes a robust positive relationship between commodity producers’ profitability growth and future returns of commodity futures. The spread portfolio that longs top-PPMG futures contracts and shorts bottom-PPMG futures contracts delivers a statistically significant average weekly return of 36 basis points. We further demonstrate that profitability is a strong SDF factor in commodity futures market. We theoretically justify our empirical findings by developing an investment-based pricing model, in which producers optimally adjust their production process by maximizing profits subject to aggregate profitability shocks. The model reproduces key empirical results through calibration and simulation.