Spatial imbalance of technology, which refers to unevenness or disproportionality in a spatial distribution of technology, is of key importance in the harmonious and balanced development of the world economy. This study is an attempt to develop a comparable map-independent analysis that measures spatial distribution, deviation angle, shift distance, direction and velocity of the gravity center (location-related spatial imbalance analysis) from an international range. Analyzing respectively on the gravity centers of different attribute values of 44 countries or regions and studying on the effects of the gravity centers of GDP, FDI and population on the technology center of gravity, it comes to the following conclusions: (1) the imbalance of spatial distribution is existing and will lasts for a long time; (2) the spatial distributions of GDP, FDI, and population don’t coincide with that of technology in longitude and latitude only except that the latitude distribution of FDI coincide with latitude and longitude distribution of technology; (3) the distributions of gravity centers of technology and population approximately record a south-east extending; (4) the distributions of gravity centers of GDP and FDI take on a loop-line movement with a clockwise rotation; (5) the gravity centers of GDP, FDI, population are positively associated with the gravity center of technology in latitude rather than in longitude. (6)Besides, the average velocity of different gravity centers is approximately 300km per year except that the gravity center of GDP shifts at an average speed of a little more than 9km per year. Combining analyses of the spatial distribution, deviation angle, shift distance, direction and velocity with the calculation of the coordinates’ correlation coefficients of the gravity centers, the hypotheses are partially supported. This study provides insight into the possible relationships between spatial distribution of technology, harmonious economic development and population spatial shift, and generates some interesting avenues for future research.