Data-factor marketization (DFM) serves as a critical driver for cultivating manufacturing-enterprise new-quality productive forces (ME-NQPF), fundamentally supporting China's transition toward high-quality economic development. Integrating matched panel data from A-share listed Chinese manufacturing firms (2011–2022) with the staggered establishment of regional data trading platforms as a quasi-natural experiment, this study employs a multi-period difference-in-differences (DID) framework to identify the causal impact of DFM on ME-NQPF. Empirical results demonstrate that DFM significantly enhances ME-NQPF, a finding that remains robust across alternative specifications and endogeneity treatments. Mechanism analysis identifies enterprise digital transformation as a pivotal mediator in this relationship, while competitive intensity is found to positively moderate the productivity gains from data marketization. Heterogeneity analysis further indicates that these effects are most pronounced among non-state-owned enterprises, technology-intensive sectors, and firms situated in China's eastern and central regions. These findings suggest that institutionalizing data-factor markets and accelerating digital integration are effective mechanisms for optimizing resource allocation and sustaining advanced industrial productivity.