We collect the geographical dataset of bank physical branch in China from 2008 to 2023, obtaining the 261,382 branches. Through careful data processing, we calculate the bank branch closure at city-level and merge it with regional entrepreneurship in China. With the panel dataset at city-industry-year level, we find that bank branch closure (BBC) significantly reduces neighbor entrepreneurship, which is proxied by the number of new firm entry. In mechanism analysis, we document that bank branch closure affects entrepreneurship through the financing channel and mobility channel. We also find that commercial bank branch closure plays a crucial role in affecting entrepreneurship. The reduction effect of BBC is more pronounced for those observations located in geographical intersections, coastal lines. Further, we explore the impact of BBC on the direction of entrepreneurship, showing that there is less new firm formation in manufacture industry after the BBC. In addition, we show that BBC may contribute to the entrepreneurship failure as well. Our findings may shed light on the policy makers, bank owners and those who want to form a new firm.